Ketamine Isomer R Powder

Ketamine is a chiral compound consisting of two isomers. “Isomers” are molecules with the same chemical formula and the term “chiral” comes from the Ancient Greek word for hand.

Like your hands, the isomers are mirror images of each other. There is a right-handed version of ketamine and a left-handed version of ketamine. These are S-ketamine and R-ketamine, also known as esketamine and arketamine, respectively. When we hear of ketamine without qualifiers, this usually refers to an equal mixture of both isomers. Ketamine Isomer R Powder

Ketamine Today 

Ketamine has been around for a long time. In 2022, it is relatively inexpensive.

Some have cynically attributed the development of esketamine to the greed of Big Pharma. As Dr. Wesley Ryan says, “This is one of the oldest tricks in the book. We see this all the time with pharmaceutical companies patenting isomers of generic drugs.”

Last year, a Canadian court even ruled that esketamine was not an “innovative drug”. Nonetheless, esketamine does appear to have some benefits over ketamine, including less drowsiness, lethargy and cognitive impairment.

As for arketamine, the FDA just gave a pharmaceutical company permission to perform clinical trials.

Unlike S-ketamine, the FDA has not yet approved R-ketamine (arketamine) as an antidepressant.

However, pre-clinical research and open-label trials indicate that R-ketamine may be superior to S-ketamine in the treatment of severe depression. Arketamine shows weaker activity at the NMDA and sigma receptors. As a result, this type of ketamine produces fewer hallucinogenic and dissociative effects than esketamine.

This makes arketamine an attractive depression treatment for many, especially since the psychoactive effects of ketamine can be off-putting to many patients. Studies have illustrated that greater mystical-type effects of ketamine lead to better therapeutic outcomes (such as in quitting an addiction).

Nonetheless, if a type of ketamine can still benefit patients without inducing intense subjective effects, this option could appeal to those struggling with depression and addiction who are hesitant about altering their minds.